Compare 576 Travel Destinations

Gatlinburg is a 4,000-person mountain resort town wedged into a Tennessee river valley right at the main entrance to Great Smoky Mountains National Park, the most-visited national park in the country at 13 million-plus visitors a year. The walkable Parkway downtown packs taffy shops, moonshine tasting rooms, ski-lift bases, and the SkyLift Park up to a 680-foot pedestrian suspension bridge (the longest in North America) all in eight blocks. Pigeon Forge and Dollywood are five miles north along US-441, and the Roaring Fork Motor Nature Trail loops 5.5 miles through old-growth forest just east of town. Closest airport is Knoxville (TYS, 1 hour 15 minutes northwest).

Central America's oldest colonial city on the shores of Lake Nicaragua. Colorful Spanish-era architecture, volcano views, and island-hopping in Las Isletas — at backpacker-friendly prices.

Mexico's second city and the capital of Jalisco, a 5-million metro that gave the country mariachi, tequila and the charreria rodeo. The historic centre runs from the twin-spired Cathedral past the Hospicio Cabanas, a UNESCO-listed neoclassical orphanage whose chapel ceiling is covered in Jose Clemente Orozco's 1939 frescoes including the Man of Fire. Tlaquepaque and Tonala sit on the southeast edge as artisan neighbourhoods of pottery, blown glass and Saturday markets. The town of Tequila is an hour west by tequila-themed train through fields of blue agave. GDL airport handles direct flights from most major US hubs.

Guanajuato is the Mexican silver-mining city that became a multicoloured riot — pink, ochre, mint, and lemon-yellow houses tumbling up the hillsides of a narrow ravine, with most of the city's traffic underground in 18th-century mine tunnels that were repurposed for cars. UNESCO inscribed the historic centre and the surrounding mines in 1988. The university (founded 1732) keeps the streets young; Diego Rivera was born here in a townhouse that's now a museum; the El Pípila monument on the hilltop gives you the photogenic panorama; and on weekend evenings the callejoneadas — student musicians in 17th-century costume leading wine-soaked walking serenades through the back alleys — are the warmest way to experience the city.

Havana is a city frozen in time — 1950s American cars cruise past crumbling colonial palaces, salsa music drifts from open doorways, and the Malecon seafront promenade is the world's longest open-air living room. Habana Vieja's restored squares contrast with raw, ungentrified neighborhoods. Mojitos, cigars, and a sense of place unlike anywhere else.

Houston is the fourth-largest US city (2.3M in the city, 7.3M in the metro) and the most diverse — more than 145 languages spoken, world-class Vietnamese, Indian, and Tex-Mex food scenes side by side. NASA Johnson Space Center sits 25 miles south, the Museum District packs 19 institutions into 1.5 square miles (the Menil Collection alone justifies the trip), and Buffalo Bayou Park has reshaped downtown with 160 acres of trail along the water. The catch: Houston is sprawling, hot from June through September, and exposed to Atlantic hurricanes in late summer.

Indianapolis is the most under-rated big city in the Midwest — the Indianapolis Motor Speedway hosts the Indy 500 (350,000 spectators, the largest single-day sporting event in the world) every Memorial Day weekend, the NCAA is headquartered downtown, and Mass Ave (Massachusetts Avenue) has emerged as one of the Midwest's best food-and-drink corridors. The downtown is genuinely walkable thanks to the 8-mile Cultural Trail loop, and the city has more memorial monument acreage than any US city outside Washington DC — Soldiers' and Sailors' on Monument Circle is the unofficial symbol.

Jacksonville is the largest city by area in the continental United States (875 square miles, after a 1968 city-county consolidation) and the most populous in Florida at roughly 1 million residents. The St. Johns River cuts the downtown in half, the Cummer Museum and MOCA cover the city's serious art interests, and the Jacksonville Zoo and Gardens is regularly ranked in the top 10 nationally. Three full Atlantic beach towns (Jacksonville Beach, Neptune Beach, Atlantic Beach) sit 18 miles east, and the St. Johns River Ferry at Mayport still carries cars across the river to Fort George Island. Amelia Island is 45 minutes north. The NFL Jaguars play at TIAA Bank Field downtown.

Kansas City is two cities (Missouri and Kansas) on opposite banks of the state line, but the Missouri side holds the heart: world-class barbecue (Joe's, Q39, Arthur Bryant's, Gates), the 18th & Vine jazz district where Charlie Parker and Count Basie made their names, the Country Club Plaza (the country's first car-oriented shopping district, 1923, modeled on Seville), and more public fountains than any city outside Rome. The food obsession runs deeper than just BBQ — Boulevard beer, KC strip steaks, and a pizza style of its own. The Chiefs' Super Bowl runs and the Royals' Kauffman Stadium round out one of the most underrated US cities.

The southernmost point in the continental US — 90 miles to Cuba, an island that seceded from the United States in 1982 (the Conch Republic) and never quite came back. Hemingway lived here and wrote some of his best work; his six-toed cats still roam his Whitehead Street home. The 1.25-mile Duval Street is the “longest bar in America”, the nightly Mallory Square sunset celebration is a 50-year-old ritual, and Fort Zachary Taylor State Park is the best beach on the island. Pair Old Town’s Conch architecture with a Yankee Freedom day trip to the remote Dry Tortugas National Park.

The 4.2-mile Strip is a self-contained universe of themed megaresorts — the Bellagio fountains, the Venetian canals, the Eiffel Tower replica, the Sphere's LED exterior. 42 million visitors a year. Beyond the casinos: the Fremont Street Experience in Downtown's vintage heart, world-class residencies (Adele, U2 at Sphere), and a surprisingly strong food-and-cocktail scene built on celebrity-chef imports. Red Rock Canyon sits 30 minutes west, the Grand Canyon 4 hours east, Zion 3 hours northeast.

LA is a sprawling mosaic — Hollywood glamour, Pacific beaches, Getty art, Griffith Observatory views, and some of the country's best Mexican and Asian food. The city sprawls but rewards exploration: Venice's boardwalk, Downtown's renaissance, Beverly Hills' polish, and canyon drives to hidden overlooks.

Louisville (locally pronounced LOO-uh-vul) is the bourbon capital of the world and the home of the Kentucky Derby — the first Saturday in May at Churchill Downs has been running uninterrupted since 1875. The Urban Bourbon Trail links 40+ bars and distilleries within the city; the Louisville Slugger factory makes the bats every MLB player swings; and NuLu has rebuilt East Market Street into a tight strip of restaurants, distilleries, and galleries. Add the Muhammad Ali Center, a passable food scene, and Frankfort Avenue's Frankfort Avenue antique row, and the city punches well above its 630,000 population.

Madison is built on a narrow isthmus between Lake Mendota and Lake Monona, with the white-granite Wisconsin State Capitol (the only state capitol built on an isthmus, and a near-twin of the US Capitol's design) anchoring the dead centre. The University of Wisconsin–Madison wraps the western lakeshore, the Dane County Farmers' Market loops the Capitol Square every Saturday April–November (the largest producer-only farmers' market in the United States), and the Memorial Union Terrace's sunburst chairs are the unofficial summer living room. Beer, cheese, brats, and lake life — Wisconsin to its core.

Memphis is the soul-music capital of the American South — Beale Street neon, Sun Studio's tiny tile-floor room where Elvis cut his first record in 1954, the Stax studio where Otis Redding and Booker T. recorded, and Graceland 9 miles south where Elvis lived from 1957 until his death in 1977. The Mississippi River bluff downtown looks across to Arkansas; the National Civil Rights Museum is built into the Lorraine Motel where Martin Luther King Jr. was assassinated in 1968. Add some of the best slow-cooked dry-rub barbecue in America (Rendezvous, Central BBQ, Payne's) and you have a city where music and history sit on every corner.

The colonial capital of Yucatán founded by Francisco de Montejo in 1542 on the site of the Maya city of T'hó — the conquistadors used dismantled Maya pyramid stones to build the cathedral, which you can still see in the walls. Mérida is consistently ranked among the safest cities in Mexico, the cultural capital of the Yucatec Maya (the only Mexican city where you regularly hear an indigenous language in everyday life), and the gateway to Chichén Itzá, Uxmal, and the Yucatán cenotes. The Paseo de Montejo is a French-influenced boulevard lined with henequen-boom mansions; the Mercado Lucas de Gálvez serves the best cochinita pibil in the country; the Sunday Bici-Ruta closes the city centre to cars. Heat April-May is brutal — visit November-February.

Mexico City is one of the world's great megacities — a sprawling, vibrant metropolis built on the ruins of the Aztec capital Tenochtitlan. The food scene rivals any city on earth (from street tacos to world-ranked restaurants), the museums are extraordinary, and the neighborhoods are endlessly walkable. A cultural powerhouse at altitude.

Miami is tropical America with a Latin pulse — pastel Art Deco along Ocean Drive, Wynwood's street-art galleries, Little Havana's dominoes and cafecito, and some of the country's best clubbing. The Everglades and Florida Keys are day-trip distance, and Miami Beach's Atlantic sand is steps from downtown.

Milwaukee earned its German-immigrant brewing reputation honestly — Pabst, Schlitz, Miller, and Blatz all started here, and the beer halls and corner taverns still anchor the city's social life. The Lake Michigan shoreline gives Milwaukee a 1,000-mile-long swimming pool, the white sail-like Calatrava-designed art museum is the most photographed building in Wisconsin, and the cobblestoned Third Ward warehouse district has become the food and craft hub. Add the Harley-Davidson Museum (the company was founded here in 1903), Bucks championship-era basketball, fish fries every Friday night, and you've got the quintessential Great Lakes city.

The Mississippi River city built around St. Anthony Falls — the only natural waterfall on the entire 2,340-mile river — with 22 lakes inside city limits, the 50-mile Grand Rounds parkway connecting them all, and the world's largest enclosed Skyway system (9.5 miles of climate-controlled second-floor corridors connecting 80 downtown blocks for the brutal winters). Prince was born and lived almost his entire life here; Paisley Park and First Avenue are the music pilgrimage sites. The Walker Art Center and Minneapolis Institute of Art (permanently free) are world-class; the Mall of America is 12 miles south. Twin city to St. Paul, 11 miles east — one airport, one transit system, no clear hierarchy between them.

Jamaica's second city and tourism capital offers white-sand beaches, reggae culture, jerk chicken, and a gateway to the Blue Mountains and Dunn's River Falls.

Montreal is the most European city in North America — French-speaking, festival-obsessed, and blessed with a food scene that rivals any major city. Old Montreal's cobblestone streets and basilica, the Plateau's colorful staircases, and the underground city are highlights. The bagels are better than New York's (don't @ us), and poutine is a religion.

Myrtle Beach is the resort capital of the 60-mile Grand Strand on the South Carolina coast and the most popular family beach vacation in the South. The 200-foot SkyWheel and the Boardwalk anchor the city center, Broadway at the Beach is the entertainment district with shops and restaurants, and the area holds more than 90 golf courses plus 50-plus miniature golf courses (a self-claimed mini-golf capital of the world). Direct flights into MYR from 30+ US cities, peak season runs April through September, and the food-and-mini-golf scene is unapologetically aimed at families and golf groups, not foodies.

Music City is equal parts bachelorette-pedal-tavern chaos on Broadway and deeply serious songwriter culture at the Bluebird Cafe and Station Inn. Hot chicken sweats at Hattie B's and Prince's, the Ryman Auditorium still hosts acoustic sets under its stained glass, and East Nashville and 12South have eclipsed downtown as the city's creative heart.