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Officially the southernmost city in the world — 'Fin del Mundo' (End of the World) — and the standard departure port for ~90% of all Antarctic Peninsula cruises (October-March, $7,000-$25,000+). The Beagle Channel (Darwin's HMS Beagle) frames the city on one side; the Martial Mountains rise on the other. Tierra del Fuego National Park (12km west) holds the southern terminus of Argentina's Ruta 3 marked 'Buenos Aires 3,063 km'. The 1902-1947 prison is now an excellent Maritime Museum. Tax-free Tierra del Fuego makes electronics and Argentine wine cheaper than mainland; Cerro Castor ski resort 26km away is the world's southernmost commercial slope.

Chile's bohemian port city — UNESCO-listed hillside neighborhoods blanketed in street art, connected by century-old funiculars, and buzzing with poets, galleries, and seafood.